Toxic Shock Syndrome (TSS): Warning Signs & What to Do

Realizing you left a tampon in too long can send your mind straight to worst-case scenarios. But your body gives clearer signals than any hour count, and most of the time, all it takes is removing it and paying attention.

You were so busy during the day, and you suddenly remember a tampon has been in longer than you meant. Now, you suddenly feel dizzy, and you can’t quite tell whether you’re coming down with something or whether your period has anything to do with it.

If you are experiencing this, the words toxic shock syndrome are probably already in your search bar. But here’s what matters. Most of the time, symptoms like these will have a much more ordinary explanation. But knowing which symptoms you can watch calmly and which ones mean you should get medical help is far more useful than counting the hours and imagining the worst.

On this page
  1. What is toxic shock syndrome?
  2. I left a tampon in too long. What should I do?
  3. What does TSS actually feel like?
  4. Could this be a bad period, flu, or stomach bug?
  5. Why are tampons blamed more?
  6. Can menstrual cups cause TSS too?
  7. Is it possible to get TSS without using tampons?
  8. What happens if doctors suspect TSS?
  9. If I’ve had TSS before, can TSS recur, and can I still use tampons?

Key takeaways

  • TSS is a rare but potentially life-threatening illness caused by toxins made by certain bacteria.
  • If a tampon has been in for more than 8 hours, remove it as soon as you notice.
  • A forgotten tampon does not automatically mean you have TSS.
  • Sudden fever, vomiting or diarrhea, dizziness or fainting, a widespread rash, severe weakness, or feeling rapidly worse are some signs for which you should seek urgent medical help.
  • Change tampons every 4 to 8 hours and use the lowest absorbency that works for your flow.
  • TSS can happen without tampon use.

What is toxic shock syndrome?

Toxic shock syndrome (TSS) is a rare but potentially life-threatening illness caused by toxins made by certain bacteria. TSS happens when certain strains of bacteria (most often Staphylococcus aureus or group A Streptococcus) produce toxins that trigger an intense reaction throughout the body.12 That reaction can lower blood pressure and affect several organs at once. That is what makes TSS different from an ordinary localized infection.

You may also come across the term staphylococcal TSS, which is the type most closely associated with menstruation and tampon use. Streptococcal TSS is linked to group A strep infections and can occur after skin, wound, or deeper tissue infections.2

“The exact bacteria matters less right now than the practical question: what should you do if a tampon has been in longer than recommended?”

I left a tampon in too long. What should I do?

Remove it as soon as possible. The FDA recommends changing tampons every 4 to 8 hours and never leaving one tampon in for more than 8 hours.1

If you have just realized it has been 9, 10, or even more hours, try not to delay it more. The 8-hour rule is a safety guideline. However, don’t worry, TSS isn’t a switch that turns itself ‘On’ after 8 hours. Several factors come into play.

How you feel makes a huge difference. If you feel completely well, an overdue tampon by itself does not mean you have toxic shock syndrome. Use another period product for the moment and pay attention to symptoms. But if you have a sudden fever, vomiting, diarrhea, dizziness, fainting, a widespread red rash, marked weakness, or you feel frighteningly ill, seek urgent medical care.13

If the tampon will not come out, or you develop fever, significant pain, unusual vaginal discharge, or another unexpected symptom, contact a healthcare professional rather than repeatedly trying to retrieve it yourself.1

Forgotten tampon and feeling well: The time alone does not diagnose TSS.

Forgotten tampon and suddenly feeling very sick: The symptom pattern matters more than the hour count. Get urgent medical assessment.

What does TSS actually feel like?

The difficult thing about early TSS is that it does not arrive wearing a name tag. At first, it can resemble the flu, a stomach bug, or another infection. The clue is often the pattern: several symptoms appear together, fairly suddenly, and you feel much sicker than you would expect from an ordinary period. Symptoms can include:

  • A sudden high fever
  • Vomiting
  • Diarrhea
  • Dizziness or fainting
  • Low blood pressure
  • Severe muscle aches
  • Confusion
  • Widespread rash that may look like sunburn13
  • Some people also develop redness of the eyes or mouth
  • Skin peeling can occur later in the illness3

That last point matters because people sometimes search for photographs of peeling skin and think, I don’t have that, so I must be okay. Do not wait for skin peeling before getting help.

One headache or one episode of nausea can have dozens of explanations. But a sudden cluster of symptoms plus rapid worsening is much more important.

Could this be a bad period, flu, or stomach bug?

Most of the time, yes. Having a fever, vomiting, diarrhea, body aches, and exhaustion don’t immediately mean that you are having toxic shock syndrome.

A group of symptoms, however, is of real concern. For example, sudden high fever with vomiting, dizziness, and widespread rash, significant weakness, or fainting are signs that should never be ignored. They indicate that something is wrong with your body. If you are confused and don’t know for sure, it’s better to ask a professional.

Reassuring signs vs. urgent warning signs

More reassuring patternUrgent warning pattern
A tampon that’s overdue, but you have no systemic symptomsSeveral symptoms appear together and worsen quickly
You otherwise feel wellSudden high fever with vomiting or diarrhea, dizziness or fainting, or severe weakness
No widespread rash, confusion, or rapid decline in overall healthA widespread sunburn-like rash, confusion, severe muscle aches, or rapid deterioration

Why are tampons blamed more?

Tampons are not toxic, and using a tampon doesn’t mean you are at a high risk for TSS.

Menstrual TSS came to public attention in the late 1970s and early 1980s when scientists identified a link between TSS and tampons, especially some highly absorbent products available at that time. Later on, changes have been made in design, labeling, safety standards, and the prevalence of TSS has been reduced drastically.14

Tampons, in the US, are now FDA-approved medical devices and safe to use.1 Skip unverified advice online and stick to these FDA-based guidelines.

  • Use the lowest absorbency that works for your flow.
  • Change tampons every 4 to 8 hours, and never leave one in for more than 8 hours.
  • If your periods have become unpredictable, the same rules still apply.
  • Use tampons only while you are actively bleeding. Don’t wear one all day “just in case” spotting might start.1

If you’re new to tampons, our guide to your first period covers how to start.

Can menstrual cups cause TSS too?

There have been cases of TSS associated with menstrual cups, but a lot less information is available compared to tampon-associated TSS.4 This does not make menstrual cups automatically unsafe.

It means that any internal product for menstruation should be used according to the manufacturer’s instructions. The FDA advises: “Wash your hands before and after handling a menstrual cup.” It also recommends following the manufacturer’s directions for washing, emptying, and reusing it.5

Don’t assume the tampon 8-hour rule automatically covers menstrual cups. Follow the instructions for the specific product you use.5

Is it possible to get TSS without using tampons?

Yes, and this is a myth that should be discussed before moving forward. Most of us think that TSS is heavily associated with tampons, but it is certainly not just a tampon illness.

It can be associated with:

  • Wounds
  • Surgery
  • Burns
  • Infections of the skin and deep tissues
  • Other bacterial infections2
  • Recent childbirth
  • A foreign body or packing such as nasal packing used for a nosebleed6

Strep TSS can also be fatal if untreated, as it rapidly advances from flu-like illness to low blood pressure and multiple organ failure.7

What happens if doctors suspect TSS?

There is no home test for TSS, but doctors will assess your symptoms and any possible wounds or existing infections you have or recently had. They will run blood tests, including tests to check organ function, cultures, and monitor vital signs, including blood pressure. Tampon use is also noted where applicable.

Treatment is usually done in hospitals and may include intravenous fluid therapy, intravenous antibiotics, blood pressure support with other medication and fluids, and treatment of affected organs where appropriate.27

If a tampon or other internal device is causing the illness, it will be removed. If some other deep tissue or wound is the source of infection, you may need a surgical approach.7

You do not need to memorize these detailed medical procedures; the most relevant point for your at-home knowledge is that TSS can become severe quickly, and early detection is key.

If I’ve had TSS before, can TSS recur, and can I still use tampons?

Yes. If you have had TSS before, it can come back, and most guidance advises against using tampons again unless your doctor specifically clears it.16 In U.S. surveillance data from 1979 to 1996, about 10 percent of women with menstrual TSS reported a previous similar illness, suggesting recurrence is possible but not typical. The exact risk for any one person can’t be pinned down, because estimates vary across studies and over time.8

Seek urgent medical care if you notice any of these signs:

  • Sudden high fever
    Vomiting or diarrhea, especially with severe weakness
    Dizziness, fainting, or feeling faint when you stand up
    A widespread bright red or sunburn-like rash
    Severe muscle aches
    Confusion13

Frequently asked questions

Not necessarily. Going past eight hours is outside FDA guidance, but the time alone does not diagnose TSS. What matters more is whether you develop a sudden cluster of symptoms such as fever, vomiting or diarrhea, dizziness or fainting, rash, or rapid worsening.

Yes, as long as the same tampon will not be in for more than 8 hours total. If you expect to sleep longer, use a pad or another external period product instead.

No; fever is the symptom of many diseases. With TSS, the illness becomes considerably more dangerous when other symptoms accompany fever.

Yes. You can develop TSS at any age, as it can occur due to non-menstrual-related reasons, especially wounds and other serious infections.

Yes. TSS is not limited to menstrual products. It can occur after recent surgery, with infected surgical wounds, and with foreign bodies or packings such as nasal packing.

TSS can progress quickly. The important clue is a sudden cluster of symptoms with rapid deterioration, rather than a single mild symptom on its own.

Not automatically. An overdue tampon by itself is not a reason to start antibiotics. Antibiotics are part of treatment when TSS or another bacterial infection is suspected or confirmed.

TSS can recur after recovery, so most guidance advises switching to pads or another external product rather than going back to tampons.6 Talk with your healthcare provider before using any internal period product again; they may clear it based on your history, but it should not be assumed.

Last medically reviewed on

References

Our commitment to accuracy is paramount; we use high-quality sources, including peer-reviewed studies, to support the facts in our articles. Learn more about our Editorial Process.

  1. U.S. Food and Drug Administration. The Facts on Tampons—and How to Use Them Safely. U.S. Food and Drug Administration. Updated December 23, 2024. Accessed August 21, 2026. fda.gov
  2. Atchade E, De Tymowski C, Grall N, Tanaka S, Montravers P. Toxic Shock Syndrome: A Literature Review. Antibiotics. 2024;13(1):96. doi.org
  3. Centers for Disease Control and Prevention. Toxic Shock Syndrome (Other Than Streptococcal) (TSS): 2011 Case Definition. CDC. Last reviewed April 16, 2021. Accessed August 21, 2026. ndc.services.cdc.gov
  4. Schlievert PM, Davis CC. Device-Associated Menstrual Toxic Shock Syndrome. Clinical Microbiology Reviews. 2020;33(3):e00032-19. doi.org
  5. U.S. Food and Drug Administration. Menstrual Cups. U.S. Food and Drug Administration. Accessed August 22, 2026. fda.gov
  6. Vyas JM. Toxic shock syndrome. MedlinePlus Medical Encyclopedia. National Library of Medicine. Reviewed May 23, 2024. medlineplus.gov
  7. Centers for Disease Control and Prevention. Clinical Guidance for Streptococcal Toxic Shock Syndrome. CDC. Updated August 5, 2025. Accessed August 21, 2026. cdc.gov
  8. Hajjeh RA, Reingold AL, Weil A, et al. Toxic Shock Syndrome in the United States: Surveillance Update, 1979–1996. Emerging Infectious Diseases. 1999;5(6):807-810. wwwnc.cdc.gov
Update history

Our team monitors the health and wellness space to keep articles current.

Current version (September 10, 2026) — Medically reviewed by Dr. Sadaf Iftikhar, MBBS, FCPS. Written by Dr. Aqsa Munir, MBBS.

Ask a Doctor

Still have questions?

Ask a doctor from Menstrual Portal. It’s free, private, and answered by someone who actually knows.